Chemistry:Pegzilarginase
| Clinical data | |
|---|---|
| Trade names | Loargys |
| Other names | AEB-1102 |
| Routes of administration | Intravenous |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| PubChem SID | |
| DrugBank | |
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| KEGG | |
| Chemical and physical data | |
| Formula | C1554H2492N416O463S6 |
| Molar mass | 34603.84 g·mol−1 |
Pegzilarginase, sold under the brand name Loargys, is a medication used for the treatment of hyperargininemia.[1][2]
The most common side effects include allergic reactions.[1]
Pegzilarginase was approved for medical use in the European Union in December 2023.[2]
Medical uses
Pegzilarginase is indicated for the treatment of arginase 1 deficiency, also known as hyperargininemia.[1][2]
Society and culture
Legal status
In October 2023, the Committee for Medicinal Products for Human Use adopted a positive opinion, recommending the granting of a marketing authorization under exceptional circumstances for the medicinal product Loargys, intended for the treatment of hyperargininemia.[1] The applicant for this medicinal product is Immedica Pharma AB.[1] Pegzilarginase was approved for medical use in the European Union in December 2023.[2]
Brand names
Pegzilarginase is the international nonproprietary name.[3]
Pegzilarginase is sold under the brand name Loargys.[1]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 "Loargys EPAR". 14 July 2016. https://www.ema.europa.eu/en/medicines/human/EPAR/loargys. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
- ↑ 2.0 2.1 2.2 2.3 2.4 "Loargys Product information". 18 December 2023. https://ec.europa.eu/health/documents/community-register/html/h1774.htm.
- ↑ "International nonproprietary names for pharmaceutical substances (INN): recommended INN: list 79". WHO Drug Information 32 (1). 2018.
External links
- "Pegzilarginase (Code C125143)". 27 November 2023. https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C125143.
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