Chemistry:Tetroxoprim
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Tetroxoprim (INN) is a derivative of trimethoprim. It was first described in 1979.[1]
Tetroxoprim is used often in combination with sulfadiazine (co-tetroxazine) for treating bacterial infections,[2][3] with brand names including Biroxin and Tibirox.
References
- ↑ "Tetroxoprim—a new inhibitor of bacterial dihydrofolate reductase". J Antimicrob Chemother 5 (B): 19–25. November 1979. doi:10.1093/jac/5.supplement_b.19. PMID 43863.
- ↑ "In vitro bacteriological investigations with tetroxoprim-sulphadiazine-correlation between inhibition zone diameter and minimum inhibitory concentration". Journal of Antimicrobial Chemotherapy 5: 37–44. 1979. doi:10.1093/jac/5.Supplement_B.37.
- ↑ "Bioequivalency studies on tablet formulation of tetroxoprim and sulphadiazine". Journal of Clinical Pharmacy and Therapeutics 17: 97–99. 1992. doi:10.1111/j.1365-2710.1992.tb01274.x.
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