Chemistry:Sulfadimidine

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Short description: Chemical compound
Sulfamethazine
Sulfadimidine.svg
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
CAS Number
PubChem CID
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Chemical and physical data
FormulaC12H14N4O2S
Molar mass278.33 g·mol−1
3D model (JSmol)
Melting point176 °C (349 °F)
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Sulfadimidine or sulfamethazine is a sulfonamide antibacterial.

There are non-standardizeda abbreviations for it as "sulfadimidine" (abbreviated SDI[1][2] and more commonly but less reliablyb SDD[3][4]) and as "sulfamethazine" (abbreviated SMT[5][6] and more commonly but less reliablyc SMZ[7][8]). Other names include sulfadimerazine, sulfadimezine, and sulphadimethylpyrimidine.[citation needed]

References

  1. "Sulfonamide residues in eggs". Acta Veterinaria Hungarica 40 (1–2): 99–106. 1992. PMID 1476095. 
  2. "Pharmacokinetic studies of sulphonamides in poultry". Indian Journal of Animal Sciences. 1988. 
  3. "[Studies on the identification of sulfadimidine in pork by high performance liquid chromatography with photodiode array detector and gas chromatograph-mass spectrometry]". Eisei Shikenjo Hokoku. Bulletin of National Institute of Hygienic Sciences (111): 61–5. 1993. PMID 7920569. 
  4. "Comparative pharmacokinetic study of four different sulfonamides in combination with trimethoprim in human volunteers". International Journal of Clinical Pharmacology, Therapy, and Toxicology 24 (1): 23–5. January 1986. PMID 3485584. 
  5. "Solvent effect on the determination of sulfamethazine by room-temperature photochemically induced fluorescence". Talanta 41 (2): 233–6. February 1994. doi:10.1016/0039-9140(94)80113-4. PMID 18965913. 
  6. "Photocatalytic oxidation of sulfamethazine". Chemosphere 60 (3): 372–80. July 2005. doi:10.1016/j.chemosphere.2004.11.069. PMID 15924956. Bibcode2005Chmsp..60..372K. 
  7. "Sulfamethazine absorption and disposition: effect of surgical procedures for gastroduodenal ulcers". Biopharmaceutics & Drug Disposition 8 (2): 115–24. Mar 1987. doi:10.1002/bdd.2510080203. PMID 3593892. 
  8. "The toxicity of sulfamethazine to Daphnia magna and its additivity to other veterinary sulfonamides and trimethoprim". Chemosphere 75 (11): 1519–24. June 2009. doi:10.1016/j.chemosphere.2009.02.002. PMID 19269673. Bibcode2009Chmsp..75.1519D. 

Further reading