Chemistry:Alatrofloxacin
From HandWiki
Alatrofloxacin (Trovan IV) is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt.[1]
Trovafloxacin and alatrofloxacin were both withdrawn from the U.S. market in June 2006 due to hepatotoxicity leading to liver transplant or death.[2][3]
See also
- Fluoroquinolones
References
- ↑ "Center for Drug Evaluation and Research – Application Number: 020759/020760 – Chemistry Review(s)". Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/nda/97/020760a_chemr.pdf.
- ↑ "Market withdrawal of new molecular entities approved in the United States from 1980 to 2009". Pharmacoepidemiology and Drug Safety 20 (7): 772–777. July 2011. doi:10.1002/pds.2155. PMID 21574210.
- ↑ "TROVAN® Tablets(trovafloxacin mesylate)TROVAN® I.V.(alatrofloxacin mesylate injection)For Intravenous Infusion". https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=da9b26bb-d2d7-4113-a0f9-c6c2280f4875&type=display.
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