Chemistry:Fluoroethyl fluoroacetate

From HandWiki
2-Fluoroethyl fluoroacetate
Names
Preferred IUPAC name
2-Fluoroethyl fluoroacetate
Other names
TL-855
Identifiers
3D model (JSmol)
ChemSpider
UNII
Properties
FCH
2
CO
2
CH
2
CH
2
F
Molar mass 124.087 g·mol−1
Appearance Liquid
Hazards
Main hazards Extremely toxic
Lethal dose or concentration (LD, LC):
8500 ug/kg (mouse, subcutaneous)[1]
1 mg/kg (oral, rats)[2]
  • 150 mg/m3, 10M (rat, inhalation)
  • 450 ug/m3 (mouse, inhalation)
  • 50 mg/m3 (rabbit, inhalation)
  • 70 mg/m3, 10M (guinea pig, inhalation)
[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Fluoroethyl fluoroacetate, or more accurately 2-fluoroethyl fluoroacetate, is an organic compound with the chemical formula FCH
2
CO
2
CH
2
CH
2
F
. It is the fluoroacetate ester of 2-fluoroethanol, or in other words, the 2-fluoroethyl ester of fluoroacetic acid. 2-Fluoroethyl fluoroacetate is two times more toxic than methyl fluoroacetate.[3]

See also

References

  1. 1.0 1.1 "2-Fluoroethyl fluoroacetate". https://pubchem.ncbi.nlm.nih.gov/compound/2-Fluoroethyl-fluoroacetate. 
  2. Kitano, Hisao; Fukui, Ken-ichi; Nozu, Ryuzaburo; Osaka, Taichiro (1955). "(85) Some Reactions of Monofluoroacetic Acid Derivatives." (in Japanese). The Journal of the Society of Chemical Industry, Japan 58 (3): 224–226. doi:10.1246/nikkashi1898.58.224. 
  3. Saunders, B. C.; Stacey, G. J. (1949). "196. Toxic fluorine compounds containing the C–F link. Part IV. (a) 2-Fluoroethyl fluoroacetate and allied compounds. (b) 2 : 2′-Difluorodiethyl ethylene dithioglycol ether". J. Chem. Soc.: 916–919. doi:10.1039/JR9490000916. 

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