Chemistry:Vilanterol
From HandWiki
Short description: Asthma drug – β2 adrenoreceptor agonist
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| Formula | C24H33Cl2NO5 |
| Molar mass | 486.43 g·mol−1 |
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Vilanterol (INN, USAN) is an ultra-long-acting β2 adrenoreceptor agonist (ultra-LABA), which was approved in May 2013 in combination with fluticasone furoate for sale as Breo Ellipta by GlaxoSmithKline for the treatment of chronic obstructive pulmonary disease (COPD).[1][2]. The combination is also approved for the treatment of asthma in Canada, Europe, Japan[3] and New Zealand.[4]
Vilanterol is available in following combinations:
- with inhaled corticosteroid fluticasone furoate—fluticasone furoate/vilanterol (trade names Breo Ellipta (United States , NZ), Relvar Ellipta (EU, Russia , Japan ))
- with muscarinic antagonist umeclidinium bromide—umeclidinium bromide/vilanterol (trade name Anoro Ellipta)
- with inhaled corticosteroid fluticasone furoate and muscarinic antagonist umeclidinium bromide—fluticasone furoate/umeclidinium bromide/vilanterol (trade name Trelegy Ellipta)
See also
- Salmeterol—a long-acting β2 adrenoreceptor agonist (LABA) with a similar backbone.
References
- ↑ "FDA approves Breo Ellipta to treat chronic obstructive pulmonary disease". https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm351664.htm.
- ↑ "Fluticasone furoate/vilanterol: a review of its use in chronic obstructive pulmonary disease". Drugs 74 (13): 1509–22. September 2014. doi:10.1007/s40265-014-0269-6. PMID 25074268.
- ↑ "Fluticasone furoate/vilanterol: a review of its use in patients with asthma". Drugs 75 (4): 407–18. March 2015. doi:10.1007/s40265-015-0354-5. PMID 25648266.
- ↑ Zealand (www.bka.co.nz), Site designed and developed by bka interactive ltd, Auckland, New (22 June 2019). "Fluticasone and vilanterol | Health Navigator NZ". https://www.healthnavigator.org.nz/medicines/f/fluticasone-plus-vilanterol/.
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