Chemistry:Ciclesonide
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Short description: Chemical compound
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| Other names | (11β, 16α)-16, 17-[[(R)-cyclohexylmethylene]bis(oxy)]-11-hydroxy-21- (2-methyl-1-oxopropoxy)- pregna-1, 4-diene-3, 20-dione |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a607008 |
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| Routes of administration | Nasal inhalation |
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| Formula | C32H44O7 |
| Molar mass | 540.697 g·mol−1 |
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Ciclesonide is a glucocorticoid used to treat asthma and allergic rhinitis. It is marketed under the brand names Alvesco for asthma and Omnaris, Omniair, Zetonna, and Alvesco[1] for hay fever in the US and Canada.
Side effects of the medication include headache, nosebleeds, and inflammation of the nose and throat linings.[2]
It was patented in 1990 and approved for medical use in 2005.[3] The drug was approved for adults and children 12 and over by the US Food and Drug Administration in October 2006.[4] It is on the World Health Organization's List of Essential Medicines.[5]
See also
- Beclomethasone dipropionate
References
- ↑ "Covis Pharma – Products". https://covispharma.com/#home-products.
- ↑ "The role of esterases in the metabolism of ciclesonide to desisobutyryl-ciclesonide in human tissue". Biochemical Pharmacology 73 (10): 1657–1664. May 2007. doi:10.1016/j.bcp.2007.01.031. PMID 17331475.
- ↑ (in en) Analogue-based Drug Discovery. John Wiley & Sons. 2006. p. 488. ISBN 9783527607495. https://books.google.com/books?id=FjKfqkaKkAAC&pg=PA488.
- ↑ "FDA News Release. FDA Approves New Treatment for Allergies". Food and Drug Administration. 2006-10-23. https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2006/ucm108773.htm.
- ↑ World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. 2021. WHO/MHP/HPS/EML/2021.02.
Further reading
- Australian Medicines Handbook. Adelaide: Australian Medicines Handbook. 2006. ISBN 0-9757919-2-3.
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