Chemistry:Enprofylline

From HandWiki
Short description: Chemical compound
Enprofylline
Skeletal formula
Space-filling model of enprofylline
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
FormulaC8H10N4O2
Molar mass194.194 g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

Enprofylline (3-propylxanthine) is a xanthine derivative used in the treatment of asthma, which acts as a bronchodilator. It acts primarily as a competitive nonselective phosphodiesterase inhibitor with relatively little activity as a nonselective adenosine receptor antagonist.[1][2]

References

  1. "Effects of enprofylline, a xanthine lacking adenosine receptor antagonism, in patients with chronic obstructive lung disease". European Journal of Clinical Pharmacology 22 (5): 395–402. 1982. doi:10.1007/bf00542541. PMID 6288396. 
  2. Laursen LC (December 1987). "Anti asthmatic effects and pharmacokinetics of enprofylline--a new xanthine derivate". Danish Medical Bulletin 34 (6): 289–97. PMID 3325233.