Biology:Hepatic fructokinase
From HandWiki
| ketohexokinase (fructokinase) | |
|---|---|
 Ketohexokinase homodimer, Human | |
| Identifiers | |
| Symbol | KHK |
| NCBI gene | 3795 |
| HGNC | 6315 |
| OMIM | 229800 |
| RefSeq | NM_006488 |
| UniProt | P50053 |
| Other data | |
| EC number | 2.7.1.3 |
| Locus | Chr. 2 p23.3-23.2 |
| Ketohexokinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.1.3 | ||||||||
| CAS number | 9030-50-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Hepatic fructokinase (or ketohexokinase) is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate.
- ATP +
[math]\displaystyle{ \longrightarrow }[/math] ADP + 
- ATP + D-fructose → ADP + D-fructose-1-phosphate[1]
Pathology
A deficiency is associated with essential fructosuria.
References
External links
- Hepatic+fructokinase at the US National Library of Medicine Medical Subject Headings (MeSH)
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