Chemistry:77-LH-28-1
From HandWiki
Short description: Chemical compound
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| Formula | C21H32N2O |
| Molar mass | 328.500 g·mol−1 |
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77-LH-28-1 is a selective agonist of muscarinic acetylcholine receptor subtype 1 (M1) discovered in 2008. It is an allosteric agonist, exhibiting over 100-fold specificity for M1 over other muscarinic receptor subtypes. 77-LH-28-1 penetrates the brain by crossing the blood–brain barrier and is therefore a useful pharmacological tool with cognition enhancing effects.[1]
References
- ↑ "Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1". British Journal of Pharmacology 154 (5): 1104–1115. July 2008. doi:10.1038/bjp.2008.152. PMID 18454168.
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