Chemistry:Alvameline

From HandWiki
Short description: Chemical compound
Alvameline
Alvameline.png
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC9H15N5
Molar mass193.254 g·mol−1
3D model (JSmol)
  (verify)

Alvameline (Lu 25-109) is a M1 receptor agonist and M2/M3 receptor antagonist[1] that was under investigation for the treatment of Alzheimer's disease, but produced poor results in clinical trials[2] and was subsequently discontinued.

See also

References

  1. "In vivo muscarinic cholinergic mediated effects of Lu 25-109, a M1 agonist and M2/M3 antagonist in vitro". Psychopharmacology 137 (3): 233–240. June 1998. doi:10.1007/s002130050615. PMID 9683000. http://link.springer.de/link/service/journals/00213/bibs/8137003/81370233.htm. Retrieved 2009-12-03. 
  2. "A bridging study of LU 25-109 in patients with probable Alzheimer's disease". Life Sciences 62 (3): 195–202. 1998. doi:10.1016/S0024-3205(97)01087-4. PMID 9488097.