Chemistry:Buclizine
From HandWiki
Short description: Chemical compound
 | |
| Clinical data | |
|---|---|
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| ATC code | |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| IUPHAR/BPS | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| ChEBI | |
| ChEMBL | |
| Chemical and physical data | |
| Formula | C28H33ClN2 |
| Molar mass | 433.04 g·mol−1 |
| 3D model (JSmol) | |
| Chirality | Racemic mixture |
| |
| |
  (what is this?) (verify) | |
Buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic, similar to meclizine.[1]
In the United Kingdom , buclizine is one of three drugs contained in Migraleve tablets, marketed by McNeil Healthcare for migraines.[2]
References
- ↑ "Buclizine". Profiles Drug Subst Excip Relat Methodol. Profiles of Drug Substances, Excipients and Related Methodology 36: 1–33. 2011. doi:10.1016/B978-0-12-387667-6.00001-4. ISBN 9780123876676. PMID 22469258.
- ↑ "Acute toxicity and analgesic action of a combination of buclizine, codeine and paracetamol ('Migraleve') in tablet and suppository form in rats". Pharmatherapeutica 4 (5): 322–31. 1985. PMID 4070325.
 |  |
