Chemistry:Fursultiamine
From HandWiki
Short description: Chemical compound
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| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Oral |
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| Formula | C17H26N4O3S2 |
| Molar mass | 398.54 g·mol−1 |
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Fursultiamine (INN; chemical name thiamine tetrahydrofurfuryl disulfide or TTFD; brand names Adventan, Alinamin-F, Benlipoid, Bevitol Lipophil, Judolor, Lipothiamine) is a medication and vitamin used to treat thiamine deficiency. Chemically, it is a disulfide derivative of thiamine and is similar in structure to allithiamine.[1]
It was synthesized in Japan in the 1960s from allithiamine for the purpose of developing forms of thiamine with improved lipophilicity for treating vitamin B1 deficiency (i.e., beriberi),[1] It was subsequently commercialized not only in Japan but also in Spain , Austria, Germany , and the United States .[2]
See also
References
- ↑ 1.0 1.1 "Thiamine tetrahydrofurfuryl disulfide: a little known therapeutic agent". Medical Science Monitor 10 (9): RA199–203. September 2004. PMID 15328496. http://www.medscimonit.com/fulltxt.php?ICID=11763.
- ↑ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. pp. 1932. ISBN 3-88763-075-0. https://books.google.com/books?id=5GpcTQD_L2oC&q=fursultiamine&pg=PA478.
Further reading
- "Thiamine tetrahydrofurfuryl disulfide: a little known therapeutic agent". Medical Science Monitor 10 (9): RA199–203. September 2004. PMID 15328496. http://www.medscimonit.com/fulltxt.php?ICID=11763.
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