Chemistry:Bleselumab

From HandWiki
Short description: Monoclonal antibody
Bleselumab
Monoclonal antibody
TypeWhole antibody
SourceHuman
TargetCD40
Clinical data
Other namesASKP1240
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6412H9906N1690O2018S38
Molar mass144175.87 g·mol−1

Bleselumab (INN;[1] development code ASKP1240) is a human monoclonal antibody designed for the prevention of organ transplant rejection.[2][3]

This drug was developed by Kyowa Kirin Pharmaceutical Development Inc.[4]

References

  1. World Health Organization (2015). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 113". WHO Drug Information 29 (2). https://www.who.int/medicines/publications/druginformation/innlists/PL113.pdf. 
  2. "Current status of costimulatory blockade in renal transplantation". Current Opinion in Nephrology and Hypertension 25 (6): 583–590. November 2016. doi:10.1097/MNH.0000000000000268. PMID 27517137. 
  3. "Costimulation Blockade in Kidney Transplantation: An Update". Transplantation 100 (11): 2315–2323. November 2016. doi:10.1097/TP.0000000000001344. PMID 27472094. 
  4. Statement On A Nonproprietary Name Adopted By The USAN Council - Bleselumab, American Medical Association.