Chemistry:Pascolizumab
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Short description: Monoclonal antibody
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| Type | Whole antibody |
| Source | Humanized (from mouse) |
| Target | IL-4 |
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Pascolizumab is a humanized monoclonal antibody for the treatment of asthma.[1] A Phase II clinical trial in patients with symptomatic glucocorticoid naive asthma was conducted in 2001/2002.[2] Development was discontinued as it showed little benefit.[3]
References
- ↑ "Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized anti-interleukin-4 antibody with therapeutic potential in asthma". Clinical and Experimental Immunology 130 (1): 93–100. October 2002. doi:10.1046/j.1365-2249.2002.01973.x. PMID 12296858.
- ↑ Clinical trial number NCT00024544 for "Pilot Study in Patients With Symptomatic Steroid-Naive Asthma" at ClinicalTrials.gov
- ↑ "Biologic targeted therapy in allergic asthma". Annals of Allergy, Asthma & Immunology 112 (2): 108 - 115. 2014. doi:10.1016/j.anai.2013.12.013.
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