Chemistry:Vatelizumab
From HandWiki
| Monoclonal antibody | |
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| Type | Whole antibody |
| Source | Humanized |
| Target | integrin alpha 2 |
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Vatelizumab is an immunomodulator. It binds to integrin alpha 2.[1]
It was withdrawn from Phase II trials for inflammatory bowel disease due to a lack of efficacy.[2]
References
- ↑ World Health Organization (2011). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 105". WHO Drug Information 25 (2). https://www.who.int/medicines/publications/druginformation/innlists/INNprepub105.pdf.
- ↑ "Inflammatory bowel disease therapies discontinued between 2009 and 2014". Expert Opin Investig Drugs 24 (7): 949–56. 2015. doi:10.1517/13543784.2015.1035432. PMID 25861835.
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