Chemistry:Clenoliximab
From HandWiki
Short description: Monoclonal antibody
| Monoclonal antibody | |
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| Type | Whole antibody |
| Source | Chimeric (primate/human) |
| Target | CD4 |
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Clenoliximab (INN[1]) is a monoclonal antibody against CD4. It acts as an immunomodulator and has been investigated for the treatment of rheumatoid arthritis.[2] The drug is a chimeric antibody from Macaca irus and Homo sapiens.[1]
References
- ↑ 1.0 1.1 World Health Organization (1997). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 77". WHO Drug Information 11 (2): 89. http://whqlibdoc.who.int/inn/proposed_lists/prop_INN_list77.pdf.
- ↑ "Antibody-mediated stripping of CD4 from lymphocyte cell surface in patients with rheumatoid arthritis". Rheumatology 42 (1): 54–61. January 2003. doi:10.1093/rheumatology/keg030. PMID 12509613.
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