Chemistry:Keliximab
From HandWiki
Short description: Monoclonal antibody
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Chimeric (primate/human) |
| Target | CD4 |
| Clinical data | |
| Routes of administration | intravenous |
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Keliximab is a monoclonal antibody for the treatment of severe chronic asthma. It suppresses the immune reaction by binding to white blood cells via the protein CD4.[1] The drug is a chimeric antibody from Macaca irus and Homo sapiens.[2]
References
- ↑ "Randomised, dose-ranging, placebo-controlled study of chimeric antibody to CD4 (keliximab) in chronic severe asthma". Lancet 352 (9134): 1109–13. October 1998. doi:10.1016/S0140-6736(97)12261-9. PMID 9798587.
- ↑ "Proposed INN List". WHO Drug Information 10 (4). 1996. https://www.who.int/medicinedocs/index/assoc/s14161e/s14161e.pdf.
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