Chemistry:Afelimomab
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Short description: Monoclonal antibody
Monoclonal antibody | |
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Type | F(ab')2 fragment |
Source | Mouse |
Target | TNFα |
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Afelimomab (MAK 195F) is an anti-TNFα monoclonal antibody. Administration of afelimomab reduces the concentration of interleukin-6 in patients with sepsis, but reduces mortality only marginally.[1][2]
References
- ↑ "Afelimomab led to a modest mortality benefit in patients with severe sepsis and elevated interleukin-6 levels". Critical Care 9 (5): E20. August 2005. doi:10.1186/cc3798. PMID 16277704.
- ↑ "Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels". Critical Care Medicine 32 (11): 2173–82. November 2004. doi:10.1097/01.CCM.0000145229.59014.6C. PMID 15640628.
Original source: https://en.wikipedia.org/wiki/Afelimomab.
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