Chemistry:Coumermycin A1
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Short description: Chemical compound
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Other names | Coumamycin |
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Formula | C55H59N5O20 |
Molar mass | 1110.092 g·mol−1 |
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Coumermycin A1 is an aminocoumarin.[1][2] Its main target is the ATPase site of the DNA gyrase GyrB subunit.[3]
See also
References
- ↑ "Genetic engineering of antibiotic biosynthesis for the generation of new aminocoumarins". Biotechnology Advances 27 (6): 1006–1014. 2009. doi:10.1016/j.biotechadv.2009.05.017. PMID 19463934.
- ↑ "Combinatorial biosynthesis, metabolic engineering and mutasynthesis for the generation of new aminocoumarin antibiotics". Current Topics in Medicinal Chemistry 8 (8): 667–79. 2008. doi:10.2174/156802608784221505. PMID 18473891.
- ↑ "Structural Basis for DNA Gyrase Interaction with Coumermycin A1". Journal of Medicinal Chemistry 62 (8): 4225–4231. April 2019. doi:10.1021/acs.jmedchem.8b01928. PMID 30920824.
Original source: https://en.wikipedia.org/wiki/Coumermycin A1.
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