Chemistry:MMPIP

From HandWiki

MMPIP is a drug used in scientific research that acts as a selective antagonist for the metabotropic glutamate receptor subtype mGluR7.[1] This receptor subtype appears to be involved in the downstream response to cocaine in the brain.[2]

References

  1. "In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists". The Journal of Pharmacology and Experimental Therapeutics 323 (1): 147–56. October 2007. doi:10.1124/jpet.107.124701. PMID 17609420. 
  2. "Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism". Neuropsychopharmacology 34 (7): 1783–96. June 2009. doi:10.1038/npp.2008.236. PMID 19158667.