Chemistry:Tilomisole
From HandWiki
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| Preferred IUPAC name
[3-(4-Chlorophenyl)[1,3]thiazolo[3,2-a] [1,3]benzimidazol-2-yl]acetic acid | |
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3D model (JSmol)
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PubChem CID
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| Properties | |
| C17H11ClN2O2S | |
| Molar mass | 342.80 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
Tilomisole (WY-18,251) is an experimental drug which acts as an immunomodulator and has been studied for the treatment of some forms of cancer.[1][2]
It can also be seen to contain the arylacetic acid moiety that is endemic to many NSAIDs, e.g. ibufenac.[citation needed]
References
- ↑ "Immunomodulating and antimetastatic activity of 3-(p-chlorophenyl) thiazolo[3,2-a]benzimidazole-2-acetic acid (Wy-18,251, NSC 310633)". Journal of Immunopharmacology 2 (4): 491–508. 1980. doi:10.3109/08923978009026408. PMID 6970786.
- ↑ "WY 18,251 (Tilomisole), an analog of levamisole: tolerability, and immune modulating effects in cancer patients". Molecular Biotherapy 4 (1): 10–4. March 1992. PMID 1385709.
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