Biology:GNA11

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Guanine nucleotide-binding protein subunit alpha-11 is a protein that in humans is encoded by the GNA11 gene. Together with GNAQ (its paralogue), it functions as a Gq alpha subunit.

See also

• Gq alpha subunit

Further reading

• "Multiplicity of mechanisms of serotonin receptor signal transduction.". Pharmacol. Ther. 92 (2–3): 179–212. 2002. doi:10.1016/S0163-7258(01)00169-3. PMID 11916537. 
• "Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells". Proc. Natl. Acad. Sci. U.S.A. 88 (9): 3907–11. 1991. doi:10.1073/pnas.88.9.3907. PMID 1902575. Bibcode: 1991PNAS...88.3907J. 
• "Ca2+ signalling in K562 human erythroleukaemia cells: effect of dimethyl sulphoxide and role of G-proteins in thrombin- and thromboxane A2-activated pathways". Biochem. J. 312 (1): 151–8. 1996. doi:10.1042/bj3120151. PMID 7492305. 
• "G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C". J. Biol. Chem. 270 (25): 15175–80. 1995. doi:10.1074/jbc.270.25.15175. PMID 7797501. 
• "Interaction between G proteins and tyrosine kinases upon T cell receptor.CD3-mediated signaling". J. Biol. Chem. 270 (51): 30635–42. 1996. doi:10.1074/jbc.270.51.30635. PMID 8530500. 
• "The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families". Proc. Natl. Acad. Sci. U.S.A. 93 (1): 116–20. 1996. doi:10.1073/pnas.93.1.116. PMID 8552586. Bibcode: 1996PNAS...93..116L. 
• "Ras involvement in signal transduction by the serotonin 5-HT2B receptor". J. Biol. Chem. 271 (6): 3141–7. 1996. doi:10.1074/jbc.271.6.3141. PMID 8621713. 
• "Specificity of G alpha q and G alpha 11 gene expression in platelets and erythrocytes. Expressions of cellular differentiation and species differences". Biochem. J. 318 (3): 1023–31. 1996. doi:10.1042/bj3181023. PMID 8836152. 
• "The human thromboxane A2 receptor alpha isoform (TP alpha) functionally couples to the G proteins Gq and G11 in vivo and is activated by the isoprostane 8-epi prostaglandin F2 alpha". J. Pharmacol. Exp. Ther. 281 (2): 957–64. 1997. doi:10.1016/S0022-3565(24)36684-4. PMID 9152406. 
• "Interaction of the G-protein G11alpha with receptors and phosphoinositidase C: the contribution of G-protein palmitoylation and membrane association". FEBS Lett. 407 (3): 257–60. 1997. doi:10.1016/S0014-5793(97)00300-1. PMID 9175863. Bibcode: 1997FEBSL.407..257W. 
• "Activation of the prostaglandin FP receptor in human granulosa cells". J. Reprod. Fertil. 111 (2): 309–17. 1998. doi:10.1530/jrf.0.1110309. PMID 9462300. 
• "Evidence for the involvement of several intracellular domains in the coupling of oxytocin receptor to G alpha(q/11)". Cell. Signal. 10 (2): 101–5. 1998. doi:10.1016/S0898-6568(97)00097-1. PMID 9481484. 
• "RGS3 inhibits G protein-mediated signaling via translocation to the membrane and binding to Galpha11". Mol. Cell. Biol. 19 (1): 714–23. 1999. doi:10.1128/MCB.19.1.714. PMID 9858594. 
• "The prostacyclin receptor is isoprenylated. Isoprenylation is required for efficient receptor-effector coupling". J. Biol. Chem. 274 (34): 23707–18. 1999. doi:10.1074/jbc.274.34.23707. PMID 10446129. 
• "Dual signaling of human Mel1a melatonin receptors via G(i2), G(i3), and G(q/11) proteins". Mol. Endocrinol. 13 (12): 2025–38. 2000. doi:10.1210/mend.13.12.0390. PMID 10598579. 
• "Calcium-sensing receptor expression and signalling in human parathyroid adenomas and primary hyperplasia". Clin. Endocrinol. 52 (3): 339–48. 2000. doi:10.1046/j.1365-2265.2000.00933.x. PMID 10718832. 
• "Functional coupling of G proteins to endothelin receptors is ligand and receptor subtype specific". Cell. Mol. Neurobiol. 20 (3): 305–17. 2000. doi:10.1023/A:1007010125316. PMID 10789830. 
• "The angiotensin II AT2 receptor is an AT1 receptor antagonist". J. Biol. Chem. 276 (43): 39721–6. 2001. doi:10.1074/jbc.M105253200. PMID 11507095.