Chemistry:Drofenine
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Short description: Chemical compound
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| Formula | C20H31NO2 |
| Molar mass | 317.473 g·mol−1 |
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Drofenine is an antimuscarinic antispasmodic drug used for relaxing smooth muscle, thereby treating conditions, such as: dysmenorrhea, and pain in the gastrointestinal tract, biliary passages, and urogenital tract. Drofenine is assumed to work by increasing the levels of the protein TRPV3.[1][2][3]
References
- ↑ "Functional and direct binding studies using subtype selective muscarinic receptor antagonists". British Journal of Pharmacology 93 (3): 491–500. March 1988. doi:10.1111/j.1476-5381.1988.tb10303.x. PMID 2897216.
- ↑ "Inhibition effects of benactyzine and drofenine on human serum butyrylcholinesterase". Archives of Biochemistry and Biophysics 386 (1): 25–9. February 2001. doi:10.1006/abbi.2000.2188. PMID 11360997.
- ↑ "Drofenine: A 2-APB Analogue with Greater Selectivity for Human TRPV3". Pharmacology Research & Perspectives 2 (5): e00062. October 2014. doi:10.1002/prp2.62. PMID 25089200.
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