3D model (JSmol)
|Molar mass||903.96 g/mol|
|Appearance||Colorless, crystalline solid|
|Solubility in ethanol and methanol||Soluble|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
epsilon-Amanitin or ε-amanitin is a cyclic peptide. It is an amatoxin, all of which are found in several members of the mushroom genus Amanita. The oral -1">50 of ε-amanitin is approximately 0.1 mg/kg.
Like other amatoxins, ε-amanitin is an inhibitor of RNA polymerase II. Upon ingestion, it binds to the RNA polymerase II enzyme which completely prevents mRNA synthesis, effectively causing cytolysis of hepatocytes (liver cells) and kidney cells.