Chemistry:EA-3580

From HandWiki
Short description: Chemical compound
EA-3580
EA-3580.png
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC18H25NO3
Molar mass303.402 g·mol−1
3D model (JSmol)
  (verify)

EA-3580 is a potent anticholinergic deliriant drug with a fairly long duration of action, related to the chemical warfare agent 3-Quinuclidinyl benzilate (QNB). It was developed under contract to Edgewood Arsenal during the 1960s as part of the US military chemical weapons program, during research to improve upon the properties of earlier agents such as QNB.

EA-3580 is closely related to the similar compound EA-3443, and has similar potency and high central to peripheral effects ratio, but with a duration of action around half as long, although effects of EA-3580 can still persist for 24 hours or more following high doses.[1][2]

See also

References

  1. "Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents". Commission on Life Sciences. The National Academies Press. 1982. pp. 207–211. http://www.nap.edu/openbook.php?record_id=740&page=207. 
  2. Chemical Warfare Secrets Almost Forgotten. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War.. ChemBooks Inc. 2006. ISBN 978-1-4243-0080-8.