Chemistry:EA-2613

EA-2613
Identifiers
3D model (JSmol)	Interactive image;
	InChI InChI=1S/C29H49N2O5P.2HI/c1-23(29(2,3)4)35-37(11,32)36-28-21-25(31(8,9)10)20-27(22-28)34-18-13-12-17-33-26-16-14-15-24(19-26)30(5,6)7;;/h14-16,19-23H,12-13,17-18H2,1-11H3;2*1H/q+2;;/p-2 Key: MHTXYQSHPNDMCA-UHFFFAOYSA-L;
	SMILES [I-].[I-].CC(C)(C)C(C)OP(=O)(C)Oc1cc([N+](C)(C)C)cc(c1)OCCCCOc2cccc(c2)[N+](C)(C)C;
Properties
Chemical formula	C28H47I2N2O5P
Molar mass	776.476 g·mol−1
Appearance	Solid
Melting point	124–126 °C (255–259 °F; 397–399 K)
Solubility in water	Soluble
Solubility	Soluble in alcohol, acetone and chloroform
Hazards
Main hazards	Extremely toxic
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	100 μg/kg (Rats, IV); 12 μg/kg (Rabbits, IV)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

EA-2613 is an extremely toxic organophosphate nerve agent. It's an extremely potent acetylcholinesterase inhibitor that is resistant to atropine and oxime treatment.^[1]

References

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Original source: https://en.wikipedia.org/wiki/EA-2613. Read more

v t e Neurotoxins
Animal	Batrachotoxin Bestoxin Birtoxin Bungarotoxin Charybdotoxin Conotoxin Fasciculin Huwentoxin Poneratoxin Saxitoxin Tetrodotoxin Vanillotoxin Spooky toxin (SsTx) Epibatidine Zetekitoxin AB Dendrotoxin
Bacterial	Botulinum toxin Tetanospasmin
Cyanotoxins	Anatoxin-a Anatoxin-a(S) BMAA Saxitoxin
Plant	Bicuculline Penitrem A Picrotoxin Strychnine Tutin Rotenone Ginkgotoxin Cicutoxin Oenanthotoxin Thujone Volkensin
Mycotoxins	Ibotenic acid Muscarine Muscimol
Pesticides	Fenpropathrin Tetramethylenedisulfotetramine Bromethalin Crimidine Methamidophos Endosulfan Fipronil Phenylsilatrane Chlorophenylsilatrane Sulfuryl fluoride Mipafox Schradan Dimefox
Nerve agents	Cyclosarin EA-3148 Novichok agent Sarin Soman Tabun VE VG VM VP VR VX GV EA-3990 EA-4056 T-1123 Octamethylene-bis(5-dimethylcarbamoxyisoquinolinium bromide) Fluorotabun Chinese VX EA-2192
Bicyclic phosphates	TBPS TBPO IPTBO
Other	Dimethylmercury Toxopyrimidine IDPN

Identifiers

3D model (JSmol)	Interactive image
InChI InChI=1S/C29H49N2O5P.2HI/c1-23(29(2,3)4)35-37(11,32)36-28-21-25(31(8,9)10)20-27(22-28)34-18-13-12-17-33-26-16-14-15-24(19-26)30(5,6)7;;/h14-16,19-23H,12-13,17-18H2,1-11H3;2*1H/q+2;;/p-2 Key: MHTXYQSHPNDMCA-UHFFFAOYSA-L
SMILES [I-].[I-].CC(C)(C)C(C)OP(=O)(C)Oc1cc([N+](C)(C)C)cc(c1)OCCCCOc2cccc(c2)[N+](C)(C)C
Properties
Chemical formula	C₂₈H₄₇I₂N₂O₅P
Molar mass	776.476 g·mol⁻¹
Appearance	Solid
Melting point	124–126 °C (255–259 °F; 397–399 K)
Solubility in water	Soluble
Solubility	Soluble in alcohol, acetone and chloroform
Hazards
Main hazards	Extremely toxic
Lethal dose or concentration (LD, LC):
LD₅₀ (median dose)	100 μg/kg (Rats, IV) 12 μg/kg (Rabbits, IV)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references