Chemistry:IARC group 2B

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Short description: Classification of agents that are possibly carcinogenic to humans

Substances, mixtures and exposure circumstances in this list have been classified by the International Agency for Research on Cancer (IARC) as group 2B:[1] The agent (mixture) is "possibly carcinogenic to humans". The exposure circumstance entails exposures that are possibly carcinogenic to humans. This category is used for agents, mixtures and exposure circumstances for which there is limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals. It may also be used when there is inadequate evidence of carcinogenicity in humans but there is sufficient evidence of carcinogenicity in experimental animals. In some instances, an agent, mixture or exposure circumstance for which there is inadequate evidence of carcinogenicity in humans but limited evidence of carcinogenicity in experimental animals together with supporting evidence from other relevant data may be placed in this group. Further details can be found in the preamble to the IARC Monographs.

This list is focusing on the hazard linked to the agents. This means that the carcinogenic agents are capable of causing cancer, but this does not take their risk into account, which is the probability of causing a cancer given the level of exposure to this carcinogenic agent.[2]

Agents and groups of agents

A

B

C

D

  • Dacarbazine
  • Dantron (Chrysazin, 1,8-Dihydroxyanthraquinone)
  • Daunomycin
  • DDT (p,p'-DDT)
  • N,N'-Diacetylbenzidine
  • 2,4-Diaminoanisole
  • 4,4'-Diaminodiphenyl ether
  • 2,4-Diaminotoluene
  • Dibenz[a,h]acridine
  • Dibenz[c,h]acridine
  • 7H-Dibenzo[c,g]carbazole
  • Dibenzo[a,h]pyrene
  • Dibenzo[a,i]pyrene
  • Dibromoacetic acid
  • Dibromoacetonitrile
  • 1,2-Dibromo-3-chloropropane
  • 2,3-Dibromopropan-1-ol
  • 1,4-Dichloro-2-nitrobenzene
  • Dichloroacetic acid
  • para-Dichlorobenzene
  • 3,3'-Dichlorobenzidine
  • 3,3'-Dichloro-4,4'-diaminodiphenyl ether
  • 1,2-Dichloroethane
  • 2,4-D (2,4-dichlorophenoxyacetic acid)
  • 1,3-Dichloropropene (technical grade)
  • 1,3-Dichloro-2-propanol
  • Dichlorvos
  • Diethanolamine
  • Di(2-ethylhexyl)phthalate
  • 1,2-Diethylhydrazine
  • Diglycidyl resorcinol ether
  • Digoxin
  • Dihydrosafrole
  • Diisopropyl sulfate
  • 3,3'-Dimethoxybenzidine (o-Dianisidine)
  • N,N-Dimethylacetamide
  • para-Dimethylaminoazobenzene
  • trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)-vinyl]-1,3,4-oxadiazole
  • 2,6-Xylidine (2,6-Dimethylaniline)
  • Dimethylarsinic acid
  • 3,3'-Dimethylbenzidine (o-Tolidine)
  • 1,1-Dimethylhydrazine
  • Dimethyl hydrogen phosphite
  • Dimethyl-p-toluidine
  • 3,7-Dinitrofluoranthene
  • 3,9-Dinitrofluoranthene
  • 1,3-Dinitropyrene
  • 1,6-Dinitropyrene
  • 1,8-Dinitropyrene
  • 2,4-Dinitrotoluene
  • 2,6-Dinitrotoluene
  • 1,4-Dioxane
  • 1,2-Diphenylhydrazine
  • Diphenylamine
  • Disperse Blue 1

E

F

  • Foreign bodies, implanted in tissues
Polymeric, prepared as thin smooth films (with the exception of poly(glycolic acid))
Metallic, prepared as thin smooth films
Metallic cobalt, metallic nickel and an alloy powder containing 66-67% nickel, 13-16% chromium and 7% iron

G

H

I

J

K

L

  • Lasiocarpine
  • Lead
  • Leucomalachite green

M

N

O

P

Q

R

S

T

U

  • Uracil mustard

V

Z


Mixtures

Exposure circumstances

  • Carpentry and joinery
  • Cobalt metal without tungsten carbide
  • Dry cleaning (occupational exposures in)
  • Firefighter (occupational exposure as)
  • Printing processes (occupational exposures in)[4][5]
  • Talc-based body powder (perineal use of)
  • Textile manufacturing industry (work in)

Notes

  • ^1 Evaluated as a group.

References

  1. ↑ "List of Classifications, Agents classified by the IARC Monographs, Volumes 1–124". IARC. July 7, 2019. https://monographs.iarc.fr/list-of-classifications. 
  2. ↑ "IARC monographs preamble (as amended in 2019)". International Agency for Research on Cancer (IARC). https://monographs.iarc.who.int/wp-content/uploads/2019/07/Preamble-2019.pdf. Retrieved August 18, 2023. "A cancer hazard is an agent that is capable of causing cancer, whereas a cancer risk is an estimate of the probability that cancer will occur given some level of exposure to a cancer hazard." 
  3. ↑ Press release No 208, 31 May 2011, IARC classifies Radiofrequency Electromagnetic Fields as possibly carcinogenic to humans
  4. ↑ "Printing Processes and Printing Inks, Carbon Black and Some Nitro Compounds". https://publications.iarc.fr/Book-And-Report-Series/Iarc-Monographs-On-The-Identification-Of-Carcinogenic-Hazards-To-Humans/Printing-Processes-And-Printing-Inks-Carbon-Black-And-Some-Nitro-Compounds-1996. 
  5. ↑ J, Wilbourn; C, Partensky; WG., Morgan (1996). "Printing Processes and Printing Inks, Carbon Black and Some Nitro Compounds". International Agency for Research on Cancer. https://www.ncbi.nlm.nih.gov/books/NBK424275/. 

External links

ja:IARC発がん性リスク一覧



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