Chemistry:Isopropyl nitrite
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Short description: Chemical compound
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| Other names | Isopropyl alcohol nitrite; nitrous acid, isopropyl ester; 1-methylethyl nitrite; 2-propyl nitrite |
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| Formula | C3H7NO2 |
| Molar mass | 89.09 g·mol−1 |
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| Density | 0.8684 g/cm3 |
| Boiling point | 40 °C (104 °F) |
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The chemical compound isopropyl nitrite (or 2-propyl nitrite) is an alkyl nitrite made from isopropanol. It is a clear pale yellow oil that is insoluble in water.[1]
Applications
Isopropyl nitrite is one of the compounds used as poppers, an inhalant drug that induces a brief euphoria. Isopropyl nitrite has largely replaced isobutyl nitrite in poppers.
Safety
Isopropyl nitrite has been associated with eye maculopathy, visual impairment with central scotomata, bilateral foveal yellow spots, and inner segment/outer segment (IS/OS) junction disruption,[2] which may be reversible.[3]
References
- ↑ Handbook of Chemistry and Physics (85th ed.). CRC Press. 2004. ISBN 978-0-8493-0485-9.
- ↑ "Adverse ophthalmic reaction in poppers users: case series of 'poppers maculopathy'". Eye 26 (11): 1479–1486. November 2012. doi:10.1038/eye.2012.191. PMID 23079752.
- ↑ "Poppers-associated retinal toxicity". The New England Journal of Medicine 363 (16): 1583–5. October 2010. doi:10.1056/NEJMc1005118. PMID 20942681.
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