Biology:Interleukin-15 receptor

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Short description: Protein complex
interleukin 15 receptor, alpha
Protein IL15RA PDB 2ers.png
Identifiers
SymbolIL15RA
NCBI gene3601
HGNC5978
OMIM601070
RefSeqNM_172200
UniProtQ13261
Other data
LocusChr. 10 p15-10p14
interleukin 2 receptor, beta
Protein IL2RB PDB 2b5i.png
Identifiers
SymbolIL2RB
Alt. symbolsCD122
NCBI gene3560
HGNC6009
OMIM146710
RefSeqNM_000878
UniProtP14784
Other data
LocusChr. 22 q13
interleukin 2 receptor, gamma (severe combined immunodeficiency)
Protein IL2RG PDB 2b5i.png
Identifiers
SymbolIL2RG
Alt. symbolsSCIDX1, IMD4
NCBI gene3561
HGNC6010
OMIM308380
RefSeqNM_000206
Other data
LocusChr. X q13

Interleukin-15 receptor is a type I cytokine receptor, binding interleukin-15. It consists of an interleukin 15 receptor, alpha subunit and shares common beta and gamma subunits with the IL-2 receptor.[1]

References

  1. ↑ "Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes". J. Biol. Chem. 270 (50): 29862–9. 1995. doi:10.1074/jbc.270.50.29862. PMID 8530383. 

External links




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