Chemistry:Clofibride
From HandWiki
Short description: Chemical compound
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| Metabolism | Hydrolyzed to clofibric acid; hepatic glucuronidation |
| Elimination half-life | 12 hours (clofibric acid) |
| Excretion | Renal (mostly) and fecal |
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| Formula | C16H22ClNO4 |
| Molar mass | 327.81 g·mol−1 |
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Clofibride is a fibrate. Clofibride is a derivative of clofibrate. In the body it is converted into 4-chlorophenoxyisobutyric acid (clofibric acid),[1] which is the true hypolipidemic agent.[2] So clofibride, just like clofibrate is a prodrug of clofibric acid.
References
- ↑ "Clofibride". https://pubchem.ncbi.nlm.nih.gov/compound/160134.
- ↑ Entry on Clofibrat. at: Römpp Online. Georg Thieme Verlag, retrieved 06. Mai 2020.
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