Chemistry:Ibrolipim
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Names | |
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Preferred IUPAC name
Diethyl ({4-[(4-bromo-2-cyanophenyl)carbamoyl]phenyl}methyl)phosphonate | |
Identifiers | |
3D model (JSmol)
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PubChem CID
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Properties | |
C19H20BrN2O4P | |
Molar mass | 451.25 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Infobox references | |
Tracking categories (test):
Ibrolipim (NO-1886) is a cholesterol lowering drug from the statin family, which acts as a lipoprotein lipase activator. The discovery of the "statin" mevalonic acid synthesis inhibitors focused new attention on control of blood lipid levels as a measure to stave off heart disease. A number of compounds have been found that treat elevated lipid levels by other diverse mechanisms. The phosphonic acid derivative ibrolipim is believed to lower those levels by accelerating fatty acid oxidation.[1]
References
- ↑ "Lipoprotein lipase activator NO-1886". Cardiovascular Drug Reviews 21 (2): 133–42. 2003. doi:10.1111/j.1527-3466.2003.tb00111.x. PMID 12847564.
![]() | Original source: https://en.wikipedia.org/wiki/Ibrolipim.
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