Chemistry:Imidafenacin
From HandWiki
Imidafenacin (INN) is a urinary antispasmodic of the anticholinergic class.[1] It is used for the treatment of urinary incontinence and related bladder issues, especially in patients with benign prostatic hyperplasia or who have had prostate surgery. Unlike most related drugs, it is orally active but still shows a rapid onset of action, which makes it more convenient to administer.[2][3][4]
References
- ↑ "Effects of imidafenacin (KRP-197/ONO-8025), a new anti-cholinergic agent, on muscarinic acetylcholine receptors. High affinities for M3 and M1 receptor subtypes and selectivity for urinary bladder over salivary gland". Arzneimittelforschung 57 (2): 92–100. 2007. doi:10.1055/s-0031-1296589. PMID 17396619.
- ↑ "Choosing the Most Efficacious and Safe Oral Treatment for Idiopathic Overactive Bladder: A Systematic Review and Network Meta-analysis". Eur Urol Focus 8 (4): 1072–1089. Jul 2022. doi:10.1016/j.euf.2021.08.011. PMID 34563481.
- ↑ "Comparison of add-on medications for persistent storage symptoms after α-blocker treatment in BPH patients - a network meta-analysis". BMC Urol 23 (1). Oct 2023. doi:10.1186/s12894-023-01327-1. PMID 37789333.
- ↑ "Efficacy and safety evaluation of imidafenacin administered twice daily for continency recovery following radical prostatectomy in prostate cancer patients: Prospective open-label case-controlled randomized trial". Investig Clin Urol 65 (5): 466–472. Sep 2024. doi:10.4111/icu.20240129. PMID 39249919.
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