Biology:Phosphomevalonate kinase
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
Generic protein structure example |
Phosphomevalonate kinase | |||||||||
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Identifiers | |||||||||
EC number | 2.7.4.2 | ||||||||
CAS number | 9026-46-4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Phosphomevalonate kinase | |
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Identifiers | |
Symbol | PMVK |
NCBI gene | 10654 |
HGNC | 9141 |
OMIM | 607622 |
RefSeq | NM_006556 |
UniProt | Q15126 |
Other data | |
EC number | 2.7.4.2 |
Locus | Chr. 1 p13-q23 |
Phosphomevalonate kinase is an enzyme (EC 2.7.4.2) in the mevalonate pathway[1][2][3] that in humans is encoded by the PMVK gene.
References
- ↑ "Mevalonic acid pyrophosphate and isopentenylpyrophosphate". The Journal of Biological Chemistry 234 (10): 2595–604. October 1959. doi:10.1016/S0021-9258(18)69744-3. PMID 13801508.
- ↑ "Biosynthesis of terpenes. V. Formation of 5-pyrophosphomevalonic acid by phosphomevalonic kinase". Archives of Biochemistry and Biophysics 83 (1): 259–67. July 1959. doi:10.1016/0003-9861(59)90031-1. PMID 13662013.
- ↑ "Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver". The Biochemical Journal 75 (3): 417–28. June 1960. doi:10.1042/bj0750417. PMID 14416398.
External links
- Phosphomevalonate+kinase at the US National Library of Medicine Medical Subject Headings (MeSH)
- Overview of all the structural information available in the PDB for UniProt: Q15126 (Phosphomevalonate kinase) at the PDBe-KB.
Original source: https://en.wikipedia.org/wiki/Phosphomevalonate kinase.
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