Biology:mir-202 microRNA precursor family
From HandWiki
| mir-202 | |
|---|---|
| Identifiers | |
| Symbol | mir-202 |
| Rfam | RF00705 |
| miRBase family | 6 |
| Other data | |
| RNA type | microRNA |
| Domain(s) | Eukaryota; |
| PDB structures | PDBe |
In molecular biology mir-202 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. The pre-miR-202 in the mouse genome is located fully within an exon, whereas in human it lies across a splice junction. This implies that human miR-202 is exposed to a negative regulation by splicing, whereas murine miR-202 is not.[1]
See also
References
- ↑ "Alternative splicing regulates biogenesis of miRNAs located across exon-intron junctions". Molecular Cell 50 (6): 869–81. June 2013. doi:10.1016/j.molcel.2013.05.007. PMID 23747012.
Further reading
- Hoheisel, Jörg D, ed (2012). "Circulating micro-RNAs as potential blood-based markers for early stage breast cancer detection". PLOS ONE 7 (1): e29770. doi:10.1371/journal.pone.0029770. PMID 22242178. Bibcode: 2012PLoSO...729770S.
- "Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma". British Journal of Cancer 105 (2): 296–303. July 2011. doi:10.1038/bjc.2011.220. PMID 21654684.
- "Integrative analysis of microRNA, mRNA and aCGH data reveals asbestos- and histology-related changes in lung cancer". Genes, Chromosomes & Cancer 50 (8): 585–97. August 2011. doi:10.1002/gcc.20880. PMID 21563230. https://zenodo.org/record/1094997.
- "Functional microRNA involved in endometriosis". Molecular Endocrinology 25 (5): 821–32. May 2011. doi:10.1210/me.2010-0371. PMID 21436257.
- "Differential mRNA expression of genes in the porcine adrenal gland associated with psychosocial stress". Journal of Molecular Endocrinology 46 (3): 165–74. June 2011. doi:10.1530/JME-10-0147. PMID 21266515.
- "MicroRNA expression changes during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal, a product of lipid peroxidation". Free Radical Biology & Medicine 46 (2): 282–8. January 2009. doi:10.1016/j.freeradbiomed.2008.10.035. PMID 19022373.
External links
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