Biology:mir-399 microRNA precursor family
From HandWiki
| mir-399 microRNA precursor family | |
|---|---|
 Predicted secondary structure and sequence conservation of mir-399 | |
| Identifiers | |
| Symbol | mir-399 |
| Rfam | RF00445 |
| miRBase | MI0001020 |
| miRBase family | MIPF0000015 |
| Other data | |
| RNA type | Gene; miRNA |
| Domain(s) | Eukaryota |
| GO | 0035195 0035068 |
| SO | 0001244 |
| PDB structures | PDBe |
mir-399 is a microRNA that was identified in both Arabidopsis thaliana and Oryza sativa computationally and was later experimentally verified. mir-399 is thought to target mRNAs coding for a phosphate transporter.[1] The mature sequence is excised from the 3' arm of the hairpin. There are multiple copies of MIR399 in each plant genome, for example A. thaliana contains six microRNA precursors that all give rise to an almost identical mature miR-399 sequence.
References
- ↑ Jones-Rhoades, MW; Bartel DP (2004). "Computational Identification of Plant MicroRNAs and Their Targets, Including a Stress-Induced miRNA". Mol Cell 14 (6): 787–799. doi:10.1016/j.molcel.2004.05.027. PMID 15200956.
Further reading
- "Target mimicry provides a new mechanism for regulation of microRNA activity". Nat. Genet. 39 (8): 1033–7. August 2007. doi:10.1038/ng2079. PMID 17643101.
External links
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