Biology:mir-BART1 microRNA precursor family

From HandWiki
mir-BART1 microRNA precursor family
RF00363.jpg
Predicted secondary structure and sequence conservation of mir-BART1
Identifiers
Symbolmir-BART1
RfamRF00363
miRBaseMI0001067
miRBase familyMIPF0000325
Other data
RNA typeGene; miRNA
Domain(s)Viruses
GO0035195 0035068
SO0001244
PDB structuresPDBe

The mir-BART1 microRNA precursor is found in Human herpesvirus 4 (Epstein–Barr virus) and Cercopithicine herpesvirus 15. mir-BART1 is found in all stages of infection but expression is significantly elevated in the lytic stage. In Epstein-Barr virus, mir-BART1 is found in the intronic regions of the BART (Bam HI-A region rightward transcript) gene whose function is unknown.[1] The mature sequence is excised from the 5' arm of the hairpin.[2]

References

  1. "VIRmiRNA: a comprehensive resource for experimentally validated viral miRNAs and their targets". Database 2014: bau103. 1 January 2014. doi:10.1093/database/bau103. PMID 25380780. 
  2. "Identification of virus-encoded microRNAs". Science 304 (5671): 734–6. April 2004. doi:10.1126/science.1096781. PMID 15118162. 

External links