Biology:mir-625 microRNA precursor family
From HandWiki
| mir-625 | |
|---|---|
| Identifiers | |
| Symbol | mir-625 |
| Rfam | RF01017 |
| miRBase family | MIPF0000534 |
| Other data | |
| RNA type | microRNA |
| Domain(s) | Eukaryota; |
| PDB structures | PDBe |
In molecular biology mir-625 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. Many microRNAs play important roles in cancer development and progression.
mir-625 and gastric cancer
mir-625 has been shown to be down regulated in gastric cancers. This is important, as mir-625 is responsible for the regulation of metastasis in gastric tumour cells, and therefore downregulation of mir-625 results in increased metastasis.[1] mir-625 is thought to act by inhibiting the ILK protein.[1]
References
Further reading
- Lau, Kin Mang, ed (2012). "Low levels of cell-free circulating miR-361-3p and miR-625* as blood-based markers for discriminating malignant from benign lung tumors". PLOS ONE 7 (6): e38248. doi:10.1371/journal.pone.0038248. PMID 22675530. Bibcode: 2012PLoSO...738248R.
- "Identification of differentially expressed microRNAs in endometrial cancer cells after progesterone treatment". International Journal of Gynecological Cancer 22 (4): 561–5. May 2012. doi:10.1097/IGC.0b013e31824927db. PMID 22543862.
- "Circulating microRNA expression is associated with genetic subtype and survival of multiple myeloma". Medical Oncology 29 (4): 2402–8. December 2012. doi:10.1007/s12032-012-0210-3. PMID 22447484.
- "MicroRNA alterations of pancreatic intraepithelial neoplasias". Clinical Cancer Research 18 (4): 981–92. February 2012. doi:10.1158/1078-0432.CCR-11-2347. PMID 22114139.
- "Differentially expressed micoRNAs in human oocytes". Journal of Assisted Reproduction and Genetics 28 (6): 559–66. June 2011. doi:10.1007/s10815-011-9590-0. PMID 21647640.
- "[Association of miRNAs expression profiles with prognosis and relapse in childhood acute lymphoblastic leukemia]". Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi 32 (3): 178–81. March 2011. PMID 21535956.
External links
 |  |
