Biology:mir-5 microRNA precursor family

From HandWiki
mir-5
Identifiers
Symbolmir-5
RfamRF00854
miRBase family2
Other data
RNA typemicroRNA
Domain(s)Eukaryota;
PDB structuresPDBe

In molecular biology mir-5 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. mir-5 has been implicated in regulation of VEGF in an experiment where a plasmid containing a cluster of mir-5, mir-10 and mir-7 was shown to down-regulate VEGF by 75%.[1] mir-5 in chicken has been implicated in targeting genes involved in metabolism.[2]

See also

External links

  1. "Adeno-associated virus-delivered polycistronic microRNA-clusters for knockdown of vascular endothelial growth factor in vivo". The Journal of Gene Medicine 14 (5): 328–38. May 2012. doi:10.1002/jgm.2623. PMID 22438271. 
  2. "Discovery of chicken microRNAs associated with lipogenesis and cell proliferation". Physiological Genomics 41 (2): 185–93. April 2010. doi:10.1152/physiolgenomics.00156.2009. PMID 20103699. 

External links