Biology:mir-166 microRNA precursor
From HandWiki
| mir-166 microRNA precursor | |
|---|---|
 Predicted secondary structure and sequence conservation of mir-166 | |
| Identifiers | |
| Symbol | mir-166 |
| Rfam | RF00075 |
| miRBase | MI0000201 |
| miRBase family | MIPF0000004 |
| Other data | |
| RNA type | Gene; miRNA |
| Domain(s) | Eukaryota |
| GO | 0035195 0035068 |
| SO | 0001244 |
| PDB structures | PDBe |
The plant mir-166 microRNA precursor is a small non-coding RNA gene. This microRNA (miRNA) has now been predicted or experimentally confirmed in a wide range of plant species.[1] microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product.[2] In this case the mature sequence comes from the 3' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences.[3] The mature products are thought to have regulatory roles through complementarity to messenger RNA.
References
- ↑ "miRNA gene family: MIR166". mirBASE. University of Manchester. http://www.mirbase.org/cgi-bin/mirna_summary.pl?fam=MIPF0000004.
- ↑ "microRNAs: tiny regulators with great potential". Cell 107 (7): 823–6. December 2001. doi:10.1016/S0092-8674(01)00616-X. PMID 11779458.
- ↑ "MicroRNAs in plants". Genes & Development 16 (13): 1616–26. July 2002. doi:10.1101/gad.1004402. PMID 12101121.
External links
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