Chemistry:Cepharanthine
From HandWiki
Short description: Chemical compound
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| Other names | Cepharantin, O-Methylcepharanoline |
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| Formula | C37H38N2O6 |
| Molar mass | 606.719 g·mol−1 |
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Cepharanthine is an antiinflammatory and antineoplastic compound isolated from Stephania.[1] Due to these modalities, it has been shown effective against HTLV in lab research. [2] Additionally, it has successfully been used to treat a diverse range of medical conditions, including radiation-induced leukopenia, idiopathic thrombocytopenic purpura, alopecia areata, alopecia pityrodes, venomous snakebites, xerostomia, sarcoidosis, refractory anemia and various cancer-related conditions. No safety issues have been observed with CEP, and side effects are very rarely reported. [3]
References
- ↑ "Cepharanthine, an alkaloid from Stephania cepharantha Hayata, inhibits the inflammatory response in the RAW264.7 cell and mouse models". Inflammation 37 (1): 235–46. February 2014. doi:10.1007/s10753-013-9734-8. PMID 24045962.
- ↑ "Synergistic inhibition of HTLV-1-infected cell proliferation by combination of cepharanthine and a tetramethylnaphthalene derivative". Anticancer Research 32 (7): 2639–45. July 2012. PMID 22753721. http://ar.iiarjournals.org/content/32/7/2639.long.
- ↑ "Therapeutic potential of the biscoclaurine alkaloid, cepharanthine, for a range of clinical conditions". Pharmacological Reports 63 (2): 337–47. 2011. doi:10.1016/S1734-1140(11)70500-X. PMID 21602589. http://www.if-pan.krakow.pl/pjp/pdf/2011/2_337.pdf.
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