Chemistry:Cepharanthine
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Cepharanthine is an antiinflammatory and antineoplastic compound isolated from Stephania.[1] Due to these modalities, it has been shown effective against viral infections such as HTLV and hantavirus in early stage research.[2][3] Additionally, it has successfully been used to treat a diverse range of medical conditions, including radiation-induced leukopenia, idiopathic thrombocytopenic purpura, alopecia areata, alopecia pityrodes, venomous snakebites, xerostomia, sarcoidosis, refractory anemia and various cancer-related conditions. No safety issues have been observed with CEP, and side effects are very rarely reported. [4]
References
- ↑ "Cepharanthine, an alkaloid from Stephania cepharantha Hayata, inhibits the inflammatory response in the RAW264.7 cell and mouse models". Inflammation 37 (1): 235–246. February 2014. doi:10.1007/s10753-013-9734-8. PMID 24045962.
- ↑ "Synergistic inhibition of HTLV-1-infected cell proliferation by combination of cepharanthine and a tetramethylnaphthalene derivative". Anticancer Research 32 (7): 2639–2645. July 2012. PMID 22753721. http://ar.iiarjournals.org/content/32/7/2639.long.
- ↑ "Screening and identification of HTNVpv entry inhibitors with high-throughput pseudovirus-based chemiluminescence". Virologica Sinica 37 (4): 531–537. August 2022. doi:10.1016/j.virs.2022.04.015. PMID 35513270.
- ↑ "Therapeutic potential of the biscoclaurine alkaloid, cepharanthine, for a range of clinical conditions". Pharmacological Reports 63 (2): 337–347. 2011. doi:10.1016/S1734-1140(11)70500-X. PMID 21602589.
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