Chemistry:Proquazone

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Short description: Nonsteroidal anti-inflammatory drug
Proquazone
Proquazone.png
Clinical data
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CAS Number
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Chemical and physical data
FormulaC18H18N2O
Molar mass278.355 g·mol−1
3D model (JSmol)
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Proquazone is a nonsteroidal anti-inflammatory drug, known as an NSAID.[1]

Uses

Proquazone is used to treat rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.[1] It has been trialed for use as pain relief for tension headaches.[2]

The recommended adult dose is around 450mg.[1]

Side Effects

Often, use of Proquazone is associated with diarrhea (up to 30% of the time).[1]

References

  1. 1.0 1.1 1.2 1.3 "Proquazone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatic diseases and pain states". Drugs 33 (5): 478–502. May 1987. doi:10.2165/00003495-198733050-00004. PMID 3297621. 
  2. "Proquazone for tension headache--a multicenter trial". Headache 25 (3): 127–133. May 1985. doi:10.1111/j.1526-4610.1985.hed2503127.x. PMID 3891682.