Chemistry:Ethenzamide

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Short description: NSAID analgesic drug
Ethenzamide
Ethenzamide.svg
Clinical data
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Chemical and physical data
FormulaC9H11NO2
Molar mass165.192 g·mol−1
3D model (JSmol)
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Ethenzamide (2-ethoxybenzamide) is a common analgesic and anti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains.[1][2] It is also an ingredient in numerous cold medications and many prescription analgesics.[citation needed] It is used as an over-the-counter drug in Japan , often in combination with caffeine and acetaminophen, where it is marketed for uses including toothache, menstrual cramps, headache, and fever.[3]

It is metabolized in vivo into salicylamide.[4]

References

  1. "Synthesis and preliminary pharmacological study of thiophene analogues of the antipyretic and analgesic agent ethenzamide". Archiv der Pharmazie 325 (2): 83–7. February 1992. doi:10.1002/ardp.19923250206. PMID 1605721. 
  2. "Frequent analgesics consumption in migraineurs: Comparison between chronic and episodic migraineurs". The Journal of Headache and Pain 5 (1): 30–35. 2004. doi:10.1007/s10194-004-0065-x. 
  3. "OTC Pain Relief Medicine in Japan". https://lifeabroad.jp/html/medical_health/pain_relief.html. 
  4. "エテンザミド". http://www-yaku.meijo-u.ac.jp/Research/Laboratory/chem_pharm/mhiramt/EText/Diseases_Drugs/ethenzamide.htm.