Chemistry:FEM-1689

From HandWiki

FEM-1689 is a drug which acts as a potent and selective sigma-2 receptor ligand with a binding affinity of 11 nM, and was developed for the treatment of neuropathic pain.[1]

References

  1. "Highly specific σ2R/TMEM97 ligand FEM-1689 alleviates neuropathic pain and inhibits the integrated stress response". Proceedings of the National Academy of Sciences of the United States of America 120 (52). December 2023. doi:10.1073/pnas.2306090120. PMID 38117854. Bibcode2023PNAS..12006090Y.