Chemistry:Caramiphen

Short description: Chemical compound

Caramiphen

Clinical data
Trade names	Carafen
ATC code	None
Identifiers
IUPAC name 2-(Diethylamino)ethyl 1-phenylcyclopentanecarboxylate
CAS Number	77-22-5
PubChem CID	6472
ChemSpider	6228
UNII	97J7NP0XJY
ChEMBL	ChEMBL61946
Chemical and physical data
Formula	C18H27NO2
Molar mass	289.419 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(OCCN(CC)CC)C2(c1ccccc1)CCCC2
InChI InChI=1S/C18H27NO2/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3 Key:OFAIGZWCDGNZGT-UHFFFAOYSA-N

Caramiphen is an anticholinergic drug used in the treatment of Parkinson's disease. In combination with phenylpropanolamine it is used as a cough suppressant and nasal decongestant to treat symptoms associated with respiratory illnesses such as cold, allergies, hay fever, and sinusitis. It was added to the British National Formulary in 1963, with a dosage of 10 to 20 mg. Side effects include nausea, dizziness, and drowsiness.

It binds to the sigma-1 receptor with an IC₅₀ value of 25 nM.