Chemistry:Cefatrizine

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Cefatrizine is a first generation broad-spectrum cephalosporin antibiotic[1] that was developed in the 1970's by GSK plc.[2] It was sold commercially by Bristol Myers Squibb in France as Cefaperos[3][4] and in Pakistan as Zanitrin,[4][5] though the subject of some clinical trials in the United States,[6] it was never brought to market there.

References

  1. ↑ "Orally active 7-phenylglycyl cephalosporins. Structure-activity studies related to cefatrizine (SK&F 60771)". The Journal of Antibiotics (Tokyo) 29 (1): 65–80. January 1976. doi:10.7164/antibiotics.29.65. PMID 776915. 
  2. ↑ Dunn GL, Hoover JR, "3-Heterocyclic thio-methylcephalosporins", US patent 3867380, published 1975-02-18, issued 1975-02-18, assigned to SmithKline Corporationand SmithKline Beecham Corp
  3. ↑ "CEFAPEROS 500 mg, gélule" (in fr). ANSM. https://archive.ansm.sante.fr/searchengine/detail/(cis)/68791749. 
  4. ↑ 4.0 4.1 "Bristol-Myers Squibb Co. Form 10-K Annual Report for the Fiscal Year Ended December 31, 1993". U.S. Securities and Exchange Commission. March 31, 1994. https://content.edgar-online.com/ExternalLink/EDGAR/0000014272-94-000003.html?hash=53fc1fa78b1cd607cd113d91996b037a5257e61bd9fc0c0ab953414b2ef47edf. 
  5. ↑ "Bristol-Myers Squibb Co. Form 10-K Annual Report for the Fiscal Year Ended December 31, 1994". U.S. Securities and Exchange Commission. March 29, 1995. https://www.sec.gov/Archives/edgar/data/14272/0000014272-95-000004.txt. 
  6. ↑ "Antibacterial Activity of Cefatrizine (BL-S 640), a New Oral Cephalosporin, In Vitro". Antimicrobial Agents and Chemotherapy 9 (3): 397–402. 1976. doi:10.1128/aac.9.3.397. PMID 1273064.