Chemistry:Simmondsin
From HandWiki
Short description: Chemical compound
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| Formula | C16H25NO9 |
| Molar mass | 375.374 g·mol−1 |
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Simmondsin is a component of jojoba seeds (pronounced "ho-HO-bah") (Simmondsia chinensis). While it had been considered toxic due to jojoba seed meal causing weight loss in animals, in recent years its appetite suppressant effect has also been researched as a potential treatment for obesity.[1] It is thought to reduce appetite by increasing levels of cholecystokinin.[2][3][4][5]
References
- ↑ "Simmondsin From Jojoba - Checked for Appetite Suppression". United States Department of Agriculture, Agricultural Research Service.. http://www.ars.usda.gov/is/AR/archive/dec00/jojoba1200.htm.
- ↑ "Devazepide reverses the anorexic effect of simmondsin in the rat". The Journal of Endocrinology 147 (3): 473–7. December 1995. doi:10.1677/joe.0.1470473. PMID 8543917.
- ↑ "Comparison of the effects of simmondsin and cholecystokinin on metabolism, brown adipose tissue and the pancreas in food-restricted rats". Hormone and Metabolic Research 30 (8): 504–8. August 1998. doi:10.1055/s-2007-978921. PMID 9761380.
- ↑ "The vagus nerve is involved in the anorexigenic effect of simmondsin in the rat". Appetite 34 (2): 147–51. April 2000. doi:10.1006/appe.1999.0299. PMID 10744903.
- ↑ "Simmondsin for weight loss in rats". International Journal of Obesity 30 (7): 1143–8. July 2006. doi:10.1038/sj.ijo.0803251. PMID 16462820.
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