Chemistry:KMUP-1

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KMUP-1
KMUP-1.svg
Names
Preferred IUPAC name
7-{2-[4-(2-Chlorophenyl)piperazin-1-yl]ethyl}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Other names
7-[2-[4-(2-Chlorophenyl)piperazinyl]ethyl]-1,3-dimethylxanthine
Identifiers
3D model (JSmol)
ChemSpider
UNII
Properties
C19H23ClN6O2
Molar mass 402.88 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

KMUP-1 is a xanthine derivative with phosphodiesterase inhibitor activity.[1]

References

  1. Liou, Shu-Fen; Hsu, Jong-Hau; Lin, I-Ling; Ho, Mei-Ling; Hsu, Pei-Chuan; Chen, Li-Wen; Chen, Ing-Jun; Yeh, Jwu-Lai (2013). "KMUP-1 suppresses RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss: roles of MAPKs, Akt, NF-κB and calcium/calcineurin/NFATc1 pathways". PLOS ONE 8 (7): e69468. doi:10.1371/journal.pone.0069468. PMID 23936022. Bibcode2013PLoSO...869468L.