Chemistry:5-HO-MET

From HandWiki

5-HO-MET, also known as 5-hydroxy-N-methyl-N-ethyltryptamine, is a psychedelic drug of the tryptamine and 5-hydroxytryptamine families related to bufotenin (5-HO-DMT).[1] It is the derivative of bufotenin in which one of the two methyl groups at the amine has been extended to an ethyl group.[1] The drug is also an analogue of methylethyltryptamine (MET), 4-HO-MET (metocin), and 5-MeO-MET.[1] 5-HO-MET was reported as a novel designer drug in Canada in 2025.[1] Its predicted log P is 1.6,[2] relative to 1.2 in the case of bufotenin.[3]

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 "New psychoactive substances (NPS) identified in Canada: Results of the online NPS survey (2020–2023)". Emerging Trends in Drugs, Addictions, and Health 5. 2025. doi:10.1016/j.etdah.2025.100178. 
  2. ↑ "3-[2-[ethyl(methyl)aminoethyl]-1H-indol-5-ol"]. https://pubchem.ncbi.nlm.nih.gov/compound/146478790. 
  3. ↑ "Bufotenine". https://pubchem.ncbi.nlm.nih.gov/compound/10257. 



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