Chemistry:5-HO-DiPT

5-HO-DiPT
Identifiers
	IUPAC name 3-(2-(diisopropylamino)ethyl)-1H-indol-5-ol;
CAS Number	36288-76-3 ;
PubChem CID	71360804;
ChemSpider	29358411;
UNII	G7I3OBF3XM;
Chemical and physical data
Formula	C16H24N2O
Molar mass	260.381 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)N(CCC1=CNC2=C1C=C(C=C2)O)C(C)C;
	InChI InChI=1S/C16H24N2O/c1-11(2)18(12(3)4)8-7-13-10-17-16-6-5-14(19)9-15(13)16/h5-6,9-12,17,19H,7-8H2,1-4H3; Key:HWOLNTJLIUHEOG-UHFFFAOYSA-N;

Short description: Chemical compound

5-HO-DiPT (5-hydroxy-N,N-di-iso-propyltryptamine) is a tryptamine derivative which acts as a serotonin receptor agonist. It is primarily known as a metabolite of the better known psychoactive drug 5-MeO-DiPT,^[1] but 5-HO-DiPT has also rarely been encountered as a designer drug in its own right.^[2] Tests in vitro show 5-HO-DiPT to have high 5-HT_2A affinity and good selectivity over 5-HT_1A,^[3] while being more lipophilic than the related drug bufotenine (5-HO-DMT), which produces mainly peripheral effects.

References

↑ "Indolealkylamines: biotransformations and potential drug-drug interactions". The AAPS Journal 10 (2): 242–53. June 2008. doi:10.1208/s12248-008-9028-5. PMID 18454322.
↑ "Analytical methods for psychoactive N,N-dialkylated tryptamines". TrAC Trends in Analytical Chemistry 29 (8): 858–869. 2010. doi:10.1016/j.trac.2010.04.008.
↑ "Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes". Neuropharmacology 29 (3): 193–8. March 1990. doi:10.1016/0028-3908(90)90001-8. PMID 2139186.

0.00

(0 votes)

Original source: https://en.wikipedia.org/wiki/5-HO-DiPT. Read more

[1] "Indolealkylamines: biotransformations and potential drug-drug interactions". The AAPS Journal 10 (2): 242–53. June 2008. doi:10.1208/s12248-008-9028-5. PMID 18454322.

[2] "Analytical methods for psychoactive N,N-dialkylated tryptamines". TrAC Trends in Analytical Chemistry 29 (8): 858–869. 2010. doi:10.1016/j.trac.2010.04.008.

[3] "Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes". Neuropharmacology 29 (3): 193–8. March 1990. doi:10.1016/0028-3908(90)90001-8. PMID 2139186.

[1]

[2]

[3]

Anonymous

Search

Chemistry:5-HO-DiPT

Namespaces

More

Page actions

See also

References

Navigation

Navigation

Help

Translate

Wiki tools

Wiki tools

Identifiers

IUPAC name 3-(2-(diisopropylamino)ethyl)-1H-indol-5-ol
CAS Number	36288-76-3^N
PubChem CID	71360804
ChemSpider	29358411
UNII	G7I3OBF3XM
Chemical and physical data
Formula	C₁₆H₂₄N₂O
Molar mass	260.381 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C)N(CCC1=CNC2=C1C=C(C=C2)O)C(C)C
InChI InChI=1S/C16H24N2O/c1-11(2)18(12(3)4)8-7-13-10-17-16-6-5-14(19)9-15(13)16/h5-6,9-12,17,19H,7-8H2,1-4H3 Key:HWOLNTJLIUHEOG-UHFFFAOYSA-N

Anonymous

Search

Chemistry:5-HO-DiPT

See also

References

Navigation

Wiki tools

Page tools

Other projects

Categories